To effectively address zoonoses and emerging infectious diseases (EIDs) at the human, animal and ecosystem interfaces, a One Health approach is being increasingly adopted, emphasizing a multisectoral and multidisciplinary approach at various. With the increasing importance of the One Health concept and need to trigger an India centric multi-stakeholder dialogue, CSFD organized the First One Health India Summit at New Delhi from 3-4 May 2018. COHEART acted as one of the partner in the summit. Renowned expert from India and outside India were the speakers for the 2-day event. The Summit catalyzed a multi-stakeholder (policymakers, researchers and industry) conversation on the emerging issue of One Health which is the latest advancement of veterinary science. The conference brought together some of the best academician’s world over and par ticipants from the Government of India and industry to discuss the future of One health and how minor changes in can affect all concerned. The attendees gained a deeper and broader understanding on how inter connected healthcare, food and environment is, and the need to encourage the collaborative efforts of multiple disciplines working locally, nationally, and globally to achieve the best health for people, animals, and our environment. The participants were drawn from DCGI, CDSCO, FSSAI, FAO, WHO India Office, NCDC, DBT, Wellcome Trust, CDC India Office, DAHD. Cornell University, TANUVAS. University of Hyderabad, National Institute of Nutrition, CFTRI, KVASU, CAR-NIHSAD, GADVASU, BHU, IVRI, AIIMS. The summit accomplished a major milestone of converging stakeholders across animal health, human health, food and agri-inputs in the Indian industry along with regulators, policy makers, international experts and leading researchers. The One Health India Summit was finally concluded after a discussion by the Power Panelists on “Science and Health Policy connectedness” in which all the panelists acknowledged that the world is moving towards a One Health and indicated a few approaches and action points for initiating One Health in India. These include the need for convergence of all sectors and share data for creating Big data and real world evidence with creation of infrastructure, systems and process in place for such surveillance, monitoring and related activities with the information being available in public domain; the need for cheaper diagnostics and data for combating AMR related concerns; enhancement of animal welfare, harmonization of regulations with priority to One Health with the support of a core group creating a policy paper across disciplines for Government of India. The summit overall, received an overwhelming response that it had served as a foundational prioritization platform highlighting the burning issues for One Health.